| Character | Voice Actor (English Original) | Notes | | :--- | :--- | :--- | | | Freddie Highmore | The brave and adventurous ten-year-old hero who returns to the world of the Minimoys. | | Princess Selenia | Selena Gomez | The warrior princess of the Minimoys. Selena Gomez replaced the original voice of Madonna for the sequel. | | Maltazard | Lou Reed | The evil emperor. Lou Reed replaced David Bowie, who voiced the character in the first film. | | Daisy | Mia Farrow | Arthur's kind and supportive grandmother. | | Grandfather Archibald | Ronald Leroy Crawford | Arthur's eccentric and wise grandfather. | | Max | Snoop Dogg | A Minimooy ally with a unique style and loyalty to Arthur. |
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