What (Arduino Uno, ESP32, PIC) are you trying to connect to the sensor?

Instead of simulating the MAX30100 sensor directly inside Proteus, connect your virtual Arduino's RX/TX pins to a COMPIM (Serial Port) component. Write a quick Python script or use a serial port tool (like Virtual Serial Port Driver) to feed realistic PPG (photoplethysmogram) heart-rate strings directly into Proteus.

Click the folder icon next to it and browse to the MAX30100_Model.hex file you downloaded in Step 1.

C:\Program Files (x86)\Labcenter Electronics\Proteus 8 Professional\Data Paste Files : Move the files into the folder and any files into the Admin Permissions

Place the and add the required 4.7kΩ I2C pull-up resistors.

+5V / +3.3V | [R] 4.7k Ohm Pull-up Resistors | SDA ------+-------> To MAX30100 SDA SCL ------+-------> To MAX30100 SCL Apply Pull-Up Resistors Open your Proteus schematic design.

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      CELLULAR AND MOLECULAR PHARMACOLOGY (First Year M.Pharm Semester 1)
      CELLULAR AND MOLECULAR PHARMACOLOGY (First Year M.Pharm Semester 1)