Software from 2001 does not have modern security patches. Running it opens your system to exploits that hackers can use to breach your computer.
Attempting to install and run software designed for Windows 98/XP on Windows 10 64-bit presents major hurdles [1].
If you own a physical or digital license for Acrobat 5.0, you are legally entitled to use Distiller 5.0. However, to run it on Windows 10 64-bit, use the method described above. Do not attempt to force-install it on native Windows 10.