You cannot patch the software. If a bug is present in that specific portable build, it will remain there forever.
You do not want to risk your project data to viruses, malware, or legal complications resulting from cracked software. Could you tell me a bit more about your specific workflow? autocad portable vs autocad
While the idea of a pocket-sized AutoCAD is appealing, using portable versions carries severe risks that professional environments cannot afford. Security Vulnerabilities You cannot patch the software